Ursolic Acid 3beta-Hydroxyurs-12-en-28-oic acid
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Business Type:Manufacturer
Country/Region:China
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Business Type:Manufacturer
Country/Region:China
Ddu Verified
HOT Rank
6/10
Name:Ursolic Acid
Synonym: 3beta-Hydroxyurs-12-en-28-oic acid
CAS:77-52-1
Molecular Formula: C30H48O3
Molecular Weight: 456.71
Melting Point:283-285 oC
Effects:Ursolic acid is a pentacyclic triterpene acid, used in cosmetics,that is also capable of inhibiting various types of cancer cells by inhibiting the STAT3 activation pathway and human fibrosarcoma cells by reducing the expression of matrix metalloproteinase-9 by acting through the glucocorticoid receptor. As medicine, it is well tolerated and can be used topically and orally.
Ursolic acid is present in many plants, including apples, basil, bilberries, cranberries, elder flower, peppermint, rosemary, lavender, oregano, thyme, hawthorn, prunes. Apple peels contain high quantity of ursolic acid and related compounds which are responsible for the anti-cancer activity of apple. Ursolic acid can also serve as a starting material for synthesis of more potent bioactive derivatives, such as anti-tumor agents.